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Flu News for Senior Citizens
As H5N1 Virus Concern Grows, U.S. Buys Additional
Influenza Vaccine
U.S. wants to prepare to protect 20 million from
pandemic
November
20, 2006 – The U.S. government has taken another step toward building a
stockpile of vaccine to protect 20 million people in the event of an
influenza pandemic. The newest vaccine purchases of 5.3 million doses
supplements the existing stockpile of 5.9 million doses of H5N1 vaccine.
Health & Human Services Secretary Mike Leavitt today announced the
department has awarded contracts totaling $199.45 million to three
vaccine makers to the 90-microgram doses.
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FLU 2005-06 |
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The H5N1 strain of avian flu has spread to more
than 40 countries and has led to the deaths of hundreds of millions of
additional birds, which has heightened concern about the possibility of
a human flu pandemic.
Furthermore, the number of avian flu cases in
humans has reached more than 250 cases in 10 countries. More than half
of those persons infected have died. To date, H5N1 avian influenza has
remained primarily an animal disease, but should the virus acquire the
ability for sustained transmission among humans, the potential for an
influenza pandemic would have grave consequences for global public
health.
The three awards by HHS include a $117.9 million
contract to sanofi pasteur for 3.7 million doses, a $40.95 million
contract to Novartis for 800,000 doses and a $40.6 million to
GlaxoSmithKline for 800,000 doses.
"Having a stockpile of influenza vaccine that may
offer protection against the H5N1 virus is an important part of our
pandemic influenza preparedness plan," Secretary Leavitt said. "These
contracts are a continuation of our aggressive multi-pronged approach to
a potentially critical public health challenge."
At two 90-microgram doses per person, these
purchases provide enough courses to vaccinate nearly 2.7 million people.
Initial clinical studies of H5N1 vaccine in humans have shown that two
90-microgram doses of the vaccine are required to stimulate a level of
immune response that researchers anticipate would provide protection for
an individual against the H5N1 strains that have been spreading among
birds in Asia.
However, further clinical testing is underway,
including the evaluation of techniques that may reduce the amount of
antigen (active ingredient) per dose needed to achieve effective
individual protection.
This additional vaccine will be placed in the
nation's Strategic National Stockpile where they will be available for
use should an influenza pandemic occur.
HHS' effort to stockpile vaccine is part of a
broader effort by the department to accelerate the development and
production of new technologies for influenza vaccines within the U.S.
Earlier this year, HHS announced a $1 billion investment to support the
advanced development of cell-based production technologies for influenza
vaccines and will help to modernize and strengthen the nation's
influenza vaccine production by creating an alternative to producing
influenza vaccines in eggs.
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