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Senior Citizen Opinions & Analysis

Claims that ‘Brain Exercise’ Does Not Slow Cognitive Decline Challenged by Major Studies

Story grabbed headlines like, ‘$80 million per year brain exercise industry a crock?; as new studies show brain training helps

By Tucker Sutherland, editor & publisher

Feb. 20, 2009 – If you want to grab the headlines, come up with something negative, counter to current thinking and challenging to something important. A study in Alzheimer’s & Dementia did just that by claiming there is no evidence supporting the benefits of “brain exercise” in slowing cognitive decline. That’s how the media saw the story. In the fine print, however, the author’s admit their review was “limited by a small, heterogeneous, and methodologically limited literature.”

The story grabbed headlines, though, like this one, “$80 million per year 'brain exercise' industry a crock?”

 

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Reuters Health, a respected source of health news, used this as their lead, “Healthy older people shouldn't bother spending money on computer games and Web sites promising to ward off mental decline…” This version was carried on Medline, the government’s chief source of health news.

What is critical to know is that this small study from Lifespan Affiliated Hospitals in Providence, Rhode Island, appears to fly in the face of tons of research from some of the most prestigious institutions in the world.

By simply engaging in cognitive exercise, you can protect against future memory loss

For example, a study released today, which is to be presented in April to the American Academy of Neurology's 61st Annual Meeting in Seattle, found participating in certain mental activities, like reading magazines or crafting in middle age or later in life, may delay or prevent memory loss.

The research involved 197 people between the ages of 70 and 89 with mild cognitive impairment, or diagnosed memory loss, and 1,124 people that age with no memory problems. Both groups answered questions about their daily activities within the past year and in middle age, when they were between 50 to 65 years old.

The study found that during later years, reading books, playing games, participating in computer activities and doing craft activities such as pottery or quilting led to a 30 to 50 percent decrease in the risk of developing memory loss compared to people who did not do those activities.

People who watched television for less than seven hours a day in later years were 50 percent less likely to develop memory loss than people who watched for more than seven hours a day.

People who participated in social activities and read magazines during middle age were about 40 percent less likely to develop memory loss than those who did not do those activities.

"This study is exciting because it demonstrates that aging does not need to be a passive process. By simply engaging in cognitive exercise, you can protect against future memory loss," said study author Yonas Geda, MD, MSc, a neuropsychiatrist at Mayo Clinic in Rochester, MN, and a member of the American Academy of Neurology.

The study was funded by the National Institutes of Health, Robert H. and Clarice Smith and Abigail Van Buren Alzheimer's Disease Research Program and the Robert Wood Johnson Foundation.

Another May Clinic study finds benefits in computer-based effort to speed brain processing

This follows more research released earlier this month saying Mayo Clinic researchers have found that healthy, older adults who participated in a computer-based training program to improve the speed and accuracy of brain processing showed twice the improvement in certain aspects of memory, compared to a control group.

"What's unique in this study is that brain-processing activities seemed to help aspects of memory that were not directly exercised by the program — a new finding in memory research," says Glenn Smith, Ph.D., Mayo Clinic neuropsychologist and lead researcher on the study.

The research, a controlled, multisite, double-blind study, will be published in the April issue of the Journal of the American Geriatrics Society.

For an hour a day, five days a week for eight weeks, study participants worked on computer-based activities in their homes. The participants, from Minnesota and California, were age 65 or older. No one had a diagnosis of cognitive impairment, such as early Alzheimer's disease.

The control group, with 245 adults, watched educational videos on art, history and literature topics. They completed quizzes on the content.

The experimental therapy group, with 242 adults, completed six auditory exercises designed to help the brain improve the speed and accuracy of processing. For example, participants were asked to distinguish between high- and low-pitched sounds. To start, the sounds were slow and distinct. Gradually, the speed increased and separation disappeared.

"The sounds go faster and faster, until it ends up sounding almost like a click," says Dr. Smith. The difficulty increases only as participants master each step with 85 percent accuracy. Other exercises, such as matching or distinguishing between similar-sounding words, for example, pop and pot, also were part of the skill building.

The commercially available program was developed by Posit Science, a San Francisco company that financed the research. Mayo Clinic researchers do not have financial ties to this business.

At the end of eight weeks, researchers used a standardized tool to measure participants' memory changes. Called the Repeatable Battery for the Assessment of Neuropsychological Status, it includes tasks such as repeating words or numbers after hearing them once.

"We found that the improvement in these skills was significantly greater in the experimental group — about double," says Dr. Smith.

Participants in the experimental group self-reported memory improvement, too, indicating the change was noticeable in day-to-day tasks.

While the study results are statistically significant, Dr. Smith says it is important to understand the extent of the memory boost. Collectively, the experimental group's memory function increased about 4 percent over the baseline measured at the study's onset. The control group's overall memory gain was about 2 percent.

But, Dr. Smith says, because participants were in generally good health, the results don't offer insights on preventing Alzheimer's or other forms of dementia.

Results indicate that aging adults may be able to make better-informed decisions about ways to improve memory.

"Brain processing speed slows as we age," says Dr. Smith. "The study indicates that choosing a memory-enhancing approach that focuses on improving brain processing speed and accuracy, rather than memory retention, may be helpful."

Yet, there's no harm in trying other approaches, he says, - even doing crosswords or playing piano, but there's little evidence these methods sustain benefits in memory.

Study debunking brain training may have been too narrowly drawn

Dr. Peter J. Snyder of Lifespan Affiliated Hospitals, senior author of the literature review challenging the benefits of brain exercise, did concede some types of "brain training" are known to help people who already have memory problems function better. But, he told Reuter’s Health that their benefits for those who don't have measurable cognitive impairment isn't clear,

Snyder says the market for these products has swelled from $2 million in 2005 to an estimated $225 million this year.

"These marketed products don't confer any additional benefit over and above being socially and intellectually active in one's normal daily life," he told Reuters.

Social and intellectual engagement in day-to-day life, from reading to grandchildren to doing crossword puzzles, is probably just as effective, or more so, than any formal brain exercise program, he added.

Reuters’ report said he further, he pointed out that these activities are free.

Snyder did put in a plug for another means of maintaining cognitive ability that is supported by substantial research – physical exercise.

Actually, the conclusion drawn by Snyder’s study is much more narrowly focused than portrayed by many of the media reports. The researchers stated, “We found no evidence that structured cognitive intervention programs delay or slow progression to AD in healthy elderly.”

They say there is no evidence that these programs slow the progression to Alzheimer’s disease, which is much more restrictive that slowing the progression of cognitive decline, which may or may not be associated with AD.

They further narrowed their conclusion to base the brain exercise results just on “healthy elderly.” Although there is, as in the examples in this article, ample evidence that training can help “healthy” older people, they may not be only the “elderly.”

Below is the actual conclusion of the Lifespan review:

“Our review was limited by a small, heterogeneous, and methodologically limited literature. Within this literature, we found no evidence that structured cognitive intervention programs delay or slow progression to AD in healthy elderly.

“Further work that accounts for the limitations of past efforts and subsequent clear and unbiased reporting to the public of the state and progress of research on this topic will help the elderly make informed decisions about a range of potential preventive lifestyle measures including cognitive intervention.”

The bottom line – before senior citizens begin throwing out their computer games and crossword puzzles, they may want to do their own search of the available research exploring the benefits of brain exercise. They may decide there are better options than doing nothing to keep an aging brain active and alert.

>> Click here to the full story by Reuters Health

 

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