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Nutrition, Vitamins & Supplements for Seniors

Age-Related Macular Degeneration Risk Lowered by Lutein and Zeaxanthin

Pigment found in spinach, egg yolk, corn protect the macula from blue light

Sept. 12, 2007 – A new study seems to confirm previous findings that consuming high levels of the plant pigments lutein and zeaxanthin may lower the risk for senior citizens of age-related macular degeneration (AMD), the leading cause of blindness in older people.

Age-related macular degeneration (AMD) occurs when the macula, the area at the back of the retina that produces the sharpest vision, deteriorates over time.

 

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Read more on Nutrition, Vitamins & Supplements

 

Lutein and its related compound zeaxanthin are highly concentrated in the macula, providing a yellow color known as the macular pigment (MP).The macular pigment protects the macula from the damaging photo-oxidative effects of blue light.

AMD is a leading cause of irreversible blindness among elderly people of European descent, according to the report in the September issue of Archives of Ophthalmology, one of the JAMA/Archives journals

The Age-Related Eye Disease Study Research Group assessed 4,519 individuals who were age 60 to 80 when they enrolled in 1992 through 1998.

At that time, photographs were taken of their retinas to determine if they had AMD, and if so, to which of four stages the condition had progressed.

The participants also completed a food frequency questionnaire that measured how often they consumed foods rich in certain vitamins, minerals and other nutrients. These included lutein, zeaxanthin, beta-carotene, lycopene and vitamins C and E.

 

Where to find Lutein

 
 

Raw Foods

Foods that are naturally rich in lutein include dark green, leafy vegetables like spinach and kale, as well as other highly colored foods such as corn and egg yolks. The average American consumes only between 1 and 2 milligrams of lutein per day – considerably less than the 4-8 milligrams consumed by following the USDA Dietary Guidelines for Americans 2005.

Vitamins and Nutritional Supplements

Lutein is found in hundreds of nutritional supplements, from multivitamins to eye care formulas to products containing lutein as the sole ingredient.

Be sure to read the label to see how much lutein is included in each dose. Lutein is usually listed in milligrams – mg – though some products list lutein in micrograms – mcg. One microgram equals one-thousandth of a milligram.

Fortified and Functional Foods

The current Natural Marketing Institute's Health and Wellness Trends study shows that a growing number of consumers are interested in the health benefits of lutein-fortified foods and beverages.

Lutein Information Bureau

 

The participants were divided into five groups based on the amount of each nutrient they consumed. Those who had the highest levels of lutein and zeaxanthin were significantly less likely than those in the group with the lowest levels to have advanced AMD.

They were also less likely to have large or numerous intermediate drusen, yellow or white deposits on the retina or optic nerve head that are a sign of AMD. No associations were seen with any of the other nutrients.

Lutein and zeaxanthin, also called carotenoids and found in yellow and dark leafy vegetables, may affect processes through which light and oxygen damage the eyes, the authors note.

"Lutein and zeaxanthin have the capacity to filter short-wavelength light associated both with photochemical damage and the generation of reactive oxygen species that attack cellular lipids, proteins and nuclear material; these carotenoids also have the capacity to reduce the potency of nascent reactive oxygen species," which damage cells, they write.

"If these cross-sectional results can be confirmed in prospective samples and experimental studies, lutein and zeaxanthin may be considered as useful agents in food or supplement-based interventions designed to reduce the risk of AMD," the authors conclude.

Editor's Note: This study was supported by contracts from the National Eye Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Md., with additional support from Bausch and Lomb, Rochester, N.Y.

 

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