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Nutrition, Vitamins & Supplements for Seniors
Western Red Meat-White Flour Diet Can Lead to Colon
Cancer, Its Return and Death
Diet high in red and processed meats, sweets and
desserts, french fries, and refined grains increases the risk of cancer
recurrence and decreases survival
 Aug. 14, 2007 Regularly eating a western diet
lots of red meat, refined grains, fat and deserts, that many senior
citizens grew up on not only increases your risk of colon cancer, but
it increases the chances that the cancer will return and you will die,
according to new research to appear in the Journal of the American
Medical Association tomorrow. The study compared these western diet
eaters with those who had diets high in fruits and vegetables, and
poultry and fish.
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Nutrition, Vitamins & Supplements |
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Previous research has indicated that diet and other
lifestyle factors have a significant influence on the risk of developing
colon cancer. However, few studies have assessed the influence of diet
on colon cancer recurrence and survival.
Jeffrey A. Meyerhardt, M.D., M.P.H., of the
Dana-Farber Cancer Institute, Boston, and colleagues examined the
influence of two distinct dietary patterns on cancer recurrence and
survival in a group of 1,009 stage III colon cancer patients (cancer
present in the colon and lymph nodes) enrolled in a clinical trial of
postoperative chemotherapy in addition to other treatment.
Patients reported dietary intake using a food
frequency questionnaire during and six months after supplemental
chemotherapy. Two major dietary patterns were identified, prudent and
Western. The prudent pattern was characterized by high intakes of fruits
and vegetables, poultry, and fish; the Western pattern was characterized
by high intakes of meat, fat, refined grains, and dessert.
Patients were followed up for cancer recurrence or
death. During a median (midpoint) follow-up of 5.3 years, 324 patients
had cancer recurrence, 223 patients died with cancer recurrence, and 28
died without documented cancer recurrence.
The researchers found that a higher intake of a
Western dietary pattern after cancer diagnosis was associated with a
significant increase in the risk of cancer recurrence or death.
Compared with patients in the lowest Western
dietary pattern quintile (bottom 20 percent), those in the highest
quintile (top 20 percent) experienced a 3.3 times higher risk for cancer
recurrence or death.
Patients in the highest quintile of Western dietary
pattern were 2.9 times more likely to have cancer recur than those in
the lowest quintile.
Similarly, a significantly higher overall risk of
death with increasing Western dietary pattern was observed. In contrast,
the prudent dietary pattern was not significantly associated with cancer
recurrence or death.
Studies have shown an improved disease-free
survival among patients who receive adjuvant chemotherapy following the
surgical resection of stage III colon cancer. This is the first study,
to our knowledge, in a potentially cured population of colon cancer
survivors to address the effect of diet.
Because this was an observational study, causality
cannot and should not be drawn from these data. Nonetheless, the data
suggest that a diet characterized by higher intakes of red and processed
meats, sweets and desserts, french fries, and refined grains increases
the risk of cancer recurrence and decreases survival. Further analyses
are under way to better delineate specific nutrients or food groupings
that may have the strongest association, the authors write.
More about grains USDA Food Pyramid
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