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Nutrition, Vitamins & Supplements for Seniors

Omega-3s Boost the Brain's Grey Matter to Improve Mood

Eating fatty fish protects senior citizens' hearts, may make them happier

March 7, 2007 – Consuming fish with omega-3 fatty acids, like salmon and tuna, may not only protect senior citizens from heart disease, it may make them happier. A previous study found people with higher blood levels of omega-3s were more agreeable and less likely to be depressed. The latest study finds omega-3 increases the grey matter in the brain that is associated with mood and behavior.

 

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The University of Pittsburgh study will be presented today by Sarah M. Conklin, Ph.D., postdoctoral scholar at the Cardiovascular Behavioral Medicine Program in the department of psychiatry at the University of Pittsburgh, at the American Psychosomatic Society’s Annual Meeting, held in Budapest, Hungary.

Animal research has shown that raising omega-3 intake leads to structural brain changes.

In the earlier study, presented by Dr. Conklin at the society’s meeting last year, Pitt researchers reported that people who had lower blood levels of omega-3 fatty acids were more likely to have a negative outlook and be more impulsive. Conversely, those with higher blood levels of omega-3s were found to be more agreeable and less likely to report mild or moderate symptoms of depression.

In the study being presented today, the researchers sought to investigate if grey matter volume was proportionally related to long-chain omega-3 intake in humans, especially in areas of the brain related to mood, helping them attempt to explain the mechanisms behind the improvement in mood often associated with long-chain omega-3 intake.

Researchers interviewed 55 healthy adult participants to determine their average intake of long-chain omega-3 fatty acids. Grey matter volume was evaluated using high-resolution structural MRI.

The researchers discovered that participants who had high levels of long-chain omega-3 fatty acid intake had higher volumes of grey matter in areas of the brain associated with emotional arousal and regulation – the bilateral anterior cingulate cortex, the right amygdala and the right hippocampus.

While this finding suggests that omega-3s may promote structural improvement in areas of the brain related to mood and emotion regulation – the same areas where grey matter is reduced in people who have mood disorders such as major depressive disorder – investigators note that more research is needed to determine whether fish consumption actually causes changes in the brain.

 

 

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