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One Alcoholic Drink Daily Helps Women Have Better Minds in Old Age

Jan. 20, 2005 – A new study published yesterday says women who want to have a good mind in their old age should drink a glass of alcoholic beverage on a daily basis.

The women who consumed a beer or a glass of wine daily tended to have the mental agility of someone a year and a half younger than non-drinkers.

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Drinking more than one glass of alcoholic beverage didn't produce a greater benefit, they said. Although, few of the nurses in the study were heavy drinkers.

Researchers at Brigham and Women's Hospital (BWH) and Harvard School of Public Health (HSPH), in an analysis between 1995 and 2001, the author’s evaluated cognitive function in 12,480 participants in the Nurses' Health Study who were 70 to 81 years old, with follow-up assessments in 11,102 two years later. They found that compared to women who were nondrinkers, older women who consumed one drink per day experienced less cognitive impairment.

Specifically, such moderate consumption of alcohol seemed to produce a 20 percent reduced risk of cognitive impairment. These findings are published in the January 20, 2005 issue of the New England Journal of Medicine.

"Much evidence has demonstrated the heart benefits of light alcohol drinking, but less research has focused on cognitive functioning. While we all continue to recommend exercising caution when consuming any type of alcohol, our study suggests that moderate consumption might provide older women some cognitive benefits. Additional research needs to be conducted to better understand the links between alcohol and cognitive function," says senior author, BWH's Francine Grodstein, ScD.

This study was released on the heels of the release of the government’s new 2005 Dietary Guidelines for Americans, which also tends to support moderate drinking. It says, “Those who choose to drink alcoholic beverages should do so sensibly and in moderation,” and defined moderation as up to one drink per day for women and up to two drinks per day for men. For purposes of explaining moderation, the guidelines count as a drink five ounces of wine, 12 ounces of regular beer or 1 1/2 ounces of 80-proof distilled spirits.

In this study, alcohol consumption data was collected as part of food-frequency questionnaires issued every few years between 1980 and 1998. Alcohol intake was measured in grams of beer, wine and liquor, with moderate consumption --one glass per day -- defined as less than 15 grams per day.

Then, from 1995-2002, women participated in telephone-based cognitive surveys in which general cognition and verbal memory and fluency were evaluated. Women who were classified as moderate drinkers -- those who consumed less than 15 grams of alcohol per day - had better mean cognitive scores than nondrinkers. In addition, researchers found no significant difference in cognitive functioning among the nondrinkers and those who consumed more than one drink per day. Also, there did not seem to be any substantial difference in the effects of different forms of alcoholic beverages.

"These findings add to the results of previous studies which assessed alcohol consumption and cognitive functioning," said HSPH's Meir Stampfer, MD and chair of the Department of Epidemiology. "Given our large study population, this body of research is now powerful enough to suggest continued research to ultimately better understand the impact moderate alcohol has on cognitive function."

Stampfer participated in an earlier study of data from the Nurses' Health Study that concluded, “Among women, adherence to lifestyle guidelines involving diet, exercise, and abstinence from smoking is associated with a very low risk of coronary heart disease.”

Loss of cognitive function in old age, especially severe cognitive loss due to Alzheimer's disease, is a serious public health problem that will only increase as the number of people in the oldest age groups increases in the United States and other developed countries,” wrote Denis A. Evans, M.D., and Julia L. Bienias, ScD., in an editorial that accompanied the study.

“Effective preventive measures are the key to coping with this potentially overwhelming problem as it emerges and are even more important than is treatment of affected persons. Unfortunately, very few effective means of either prevention or treatment have been identified to date. Studies that provide clues about prevention are therefore welcome.”

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