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New Aggressive Cholesterol Guidelines Questioned After Reports on Drug Company Financial Support for Authors

July 17, 2004 - Consumer groups are aggressively questioning the credibility of a government-backed group that has recommended more aggressive treatment of bad cholesterol with more drug therapy. The doubts developed after it was revealed that substantial financial support has been provided most of the authors by the companies that make the cholesterol drugs.

Go to original story about the new guidelines

 

The only author not receiving pharmaceutical company supports was the coordinator James Cleeman, M.D.

These charges began to emerge last week after the nonprofit Center for Science in the Public Interest released a study showing medical journals often fail to reveal the financial conflicts of their authors. (Report Faults Scientific Journals on Financial Disclosure) Newsday was the first to report on the financial ties on Thursday.  

The National Heart, Lung and Blood Institute (NHLBI) reacted on Friday by posting on the Web information on the financial support provided to the authors of the study they sponsored. It shows that eight of the nine authors have received money from cholesterol drug makers, including Pfizer Inc., Merck & Co., Bristol-Myers Squibb and AstraZeneca LP. (Web page - click here)

Financial Disclosure Released by NHLBI

>> Dr. Grundy has received honoraria from Merck, Pfizer, Sankyo, Bayer, Merck/Schering-Plough, Kos, Abbott, Bristol-Myers Squibb, and AstraZeneca; he has received research grants from Merck, Abbott, and Glaxo Smith Kline.

 

>> Dr. Cleeman has no financial relationships to disclose.

 

>> Dr. Bairey Merz has received lecture honoraria from Pfizer, Merck, and Kos; she has served as a consultant for Pfizer, Bayer, and EHC (Merck); she has received unrestricted institutional grants for Continuing Medical Education from Pfizer, Procter & Gamble, Novartis, Wyeth, AstraZeneca, and Bristol-Myers Squibb Medical Imaging; she has received a research grant from Merck; she has stock in Boston Scientific, IVAX, Eli Lilly, Medtronic, Johnson & Johnson, SCIPIE Insurance, ATS Medical, and Biosite.

 

>> Dr. Brewer has received honoraria from AstraZeneca, Pfizer, Lipid Sciences, Merck, Merck/Schering-Plough, Fournier, Tularik, Esperion, and Novartis; he has served as a consultant for AstraZeneca, Pfizer, Lipid Sciences, Merck, Merck/Schering-Plough, Fournier, Tularik, Sankyo, and Novartis.

 

>> Dr. Clark has received honoraria for educational presentations from Abbott, AstraZeneca, Bristol-Myers Squibb, Merck, and Pfizer; he has received grant/research support from Abbott, AstraZeneca, Bristol-Myers Squibb, Merck, and Pfizer.

 

>> Dr. Hunninghake has received honoraria for consulting and speakers bureau from AstraZeneca, Merck, Merck/Schering-Plough, and Pfizer, and for consulting from Kos; he has received research grants from AstraZeneca, Bristol-Myers Squibb, Kos, Merck, Merck/Schering-Plough, Novartis, and Pfizer.

 

>> Dr. Pasternak has served as a speaker for Pfizer, Merck, Merck/Schering-Plough, Takeda, Kos, BMS-Sanofi, and Novartis; he has served as a consultant for Merck, Merck/Schering-Plough, Sanofi, Pfizer Health Solutions, Johnson & Johnson-Merck, and AstraZeneca.

 

>> Dr. Smith has received institutional research support from Merck; he has stock in Medtronic and Johnson & Johnson.

 

>> Dr. Stone has received honoraria for educational lectures from Abbott, AstraZeneca, Bristol-Myers Squibb, Kos, Merck, Merck/Schering-Plough, Novartis, Pfizer, Reliant, and Sankyo; he has served as a consultant for Abbott, Merck, Merck/Schering-Plough, Pfizer, and Reliant.

 

http://www.nhlbi.nih.gov/guidelines/cholesterol/atp3upd04_disclose.htm

 

More: Groups blast new cholesterol guidelines
Arizona Daily Sun

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