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Senior Citizen Health & Medicine
Prostate Cancer Increases Hip Fracture Risk by Eight
for 'Almost' Senior Citizens
Just being 50+ with prostate cancer increases hip
fracture risk by 4
 Oct. 11, 2007 - Men over age 50 who have prostate
cancer are four times more likely to suffer a hip fracture, but this
ratio shoots up to eight times for early baby boomers and other older
men on the verge of becoming senior citizens at age 65.
Danish researchers looked at 62,865 men aged 50 and
over, with an average age of just under 67 and found this staggering
number of hip fractures in those aged 50 to 65 that had prostate cancer.
The report in the October issue of the urology
journal BJU International says 15,716 had suffered a fracture of some
description and 47,149 formed the non-fracture control group.
They discovered that prostate cancer made men 1.8
times more likely overall to suffer a fracture and 3.7 times as likely
to suffer from a hip fracture.
But the hip fracture risk was eight times higher in
men from 50 to 65 years of age. No increased risk of vertebral fractures
was found by the research.
“Our study showed that more than three per cent of
hip fractures in men aged 50 and over can be attributed to prostate
cancer” says lead researcher Dr Bo Abrahamsen from Copenhagen University
Hospital, Gentofte.
“And the risk remains even when men have recovered
from the disease.”
The researchers - urologists and endocrinologists
from Danish hospitals attached to the University of Southern Denmark and
Copenhagen University - now plan to establish a multi-centre initiative
focusing on the early diagnosis and treatment of osteoporosis in men
with prostate cancer.
“Prostate cancer is now the cancer that men are
most likely to develop and is a leading cause of male deaths in Europe
and the USA” stresses Dr Abrahamsen.
“American research has also shown that men have a
17 per cent chance of prostate cancer during their lifetime. And Danish
research has discovered that deaths from the disease have more than
tripled since the Second World War.
“Medical advances are improving survival rates, but
the downside is that treatment can lead to osteoporosis, where the bone
loses density and becomes more fragile. This is turn increases the risk
of fractures.”
The researchers used data from the Danish National
Hospital Discharge Register, the National Bureau of Statistics and the
National Prescription Database to identify patients aged 50 and over who
had suffered a fracture. They then used the same data to identify an
age-matched control group.
“Our research showed that the increased fracture
risk became apparent in the early stages after diagnosis and remained
pronounced even in long-term survivors” says Steen Walter, Professor of
Urology at Odense University Hospital.
“Men who received hormone therapy (ADT) or had
their testicles surgically removed to slow the progression of the
disease were 1.7 times more likely to suffer a fracture.”
The authors point out that the research only
covered the 15 per cent of ADT doses issued on prescription. The
majority of the doses are issued by hospital departments, which means
they cannot be traced to individual patients. So the actual impact of
ADT on national fracture levels could be even greater.
Other issues were also found to lead to increased
fracture rates.
“The study showed that the men in the fracture
group were almost three times as likely as the control group to have
suffered a previous fracture. They were also more likely to live alone
and be in a lower income group” says Dr Abrahamsen.
Editor’s Notes
Established in 1929, BJU International is published
12 times a year by Wiley-Blackwell and edited by Professor John
Fitzpatrick from University College Dublin, Ireland. It provides its
international readership with invaluable practical information on all
aspects of urology, including original and investigative articles and
illustrated surgery.
www.bjui.org
Links to more SeniorJournal.com reports on
Prostate Cancer:
Cancer Cells Zapped by Electrical Impulses with Invention by Engineers
Clinical trials come next to test on prostate cancer victims
July 6, 2007
Researchers Say They
Have Found a Better Test for Prostate Cancer?
April 26, 2007
Proteins from Inflammation are 'Smoking Gun' in Spread of Prostate
Cancer
March 19, 2007
Obesity and
Prostate Cancer a Deadly Combination, Study Finds
March 15, 2007
Seniors May Increase Risk of Heart Disease from Prostate Cancer
Treatment
Feb. 26, 2007
Prostate Cancer
Patients Have High Survival Rates with Seed Implants
January 31, 2007
Radiation Therapy
Combo Cures Prostate Cancer Long-Term
January 4, 2007
Lack
of Sons Puts Men at Higher Risk for Prostate Cancer Says New Study
January 3, 2007
Elderly Men
Survive Prostate Cancer 'Significantly' Longer if Treated
December 22, 2006
Octogenarians Not Too Old for Cancer Surgery, Say Mayo Clinic
Researchers
November 27, 2006
Prostate
Cancer Studies Find Benefit to Radiation, No Harm in Testosterone
Replacement in Older Men
November 14, 2006
Prostate
Cancer Cells Killed by Protein Made by the Cancer
November 10, 2006
Researchers
Urge New Approach to Prostate Cancer Screening with Early PSA Base
November 1, 2006
Prostate Cancer Appears Cured in 89 Percent of Men Treated with IMRT
September 27, 2006
PSA of
Prostate Cancer Victims Can Predict How Long They Will Survive
August 25, 2006
Large Study Finds Some Prostate Cancer Patients
Possibly Overtreated
August 15, 2006
Plant-Based Diet with Stress Reduction Slows
Progression of Prostate Cancer
August 15, 2006 - Also in this news report you will find links
to more associations between prostate cancer and nutrition and
supplements.
Prostate Cancer Cells Killed by RNA-Based Drug
August 10, 2006
Men Found with Prostate Cancer Rush to Judgment on
Treatment
June 26, 2006
Potential of Prostate Cancer Spread Detected Early
by New Test
June 21, 2006
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