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Senior Citizen Health & Medicine

Skyrocketing Hospital Medication Errors Can Be Reduced 66%, Says New Study

Senior citizens most at risk as largest medication consumers

June 27, 2007 – The rate of medication errors experienced by hospitals has skyrocketed from only 5 percent in 1992 to nearly 25 percent today – a deadly consequence for many senior citizens, who are most likely to fall victims to medication mistakes. A study from the University of Minnesota has found a rather easy way to decrease these errors by as much as 66 percent.

 

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Doctors are famous for sloppy scribbling — and handwritten prescriptions lead to thousands of medication errors each year. Electronics to the rescue: U.S. hospitals that switched to computerized physician order entry systems saw a 66 percent drop in prescription errors, according to the new review of studies.

Illegible handwriting and transcription errors are responsible for as much as 61 percent of medication errors in hospitals. A simple mistake such as putting the decimal point in the wrong place can have serious consequences because a patient’s dosage could be 10 times the recommended amount.

Drugs with similar names are another common source of error, such as the pain medication Celebrex and the antidepressant Celexa, or the tranquilizer Zyprexa and the antihistamine Zyrtec.

“These medication errors are very painful for doctors, as well as the patients. Nobody wants to make a mistake,” said Tatyana Shamliyan, lead review author and a research associate at the University of Minnesota School of Public Health.

The incidence of medication errors can be reduced by implementing a computerized physician order entry (CPOE) system, according to a review of several studies conducted by the researchers.

The review, recently published in the online journal Health Services Research, analyzed 12 studies conducted between 1990 and 2005 that compared the number of handwritten and computerized medication errors made by hospital physicians.

Medication errors include prescribing the wrong drug, ordering an inaccurate dosage, or administering a drug at the wrong time. These mistakes dropped by as much as 66 percent in United States hospitals that switched to a CPOE system.

Illegible handwriting and transcription errors account for more than 60 percent of medication errors.

“Most errors typically go undetected unless they led to an adverse event,” said review co-author Robert Kane.

In addition to improving patient safety, computerized systems make life easier for pharmacists. “They don’t have to decipher the chicken scratch,” said Karl Gumpper, director of the pharmacy informatics and technology section of the American Society of Health-System Pharmacists, based in Bethesda, Md. Pharmacists frequently have to call the prescribing doctor or interview the patient because of problems in deciphering handwriting.

Currently, only about 9 percent of hospitals have computerized prescription systems. Some hospitals have stand-alone systems, while others have computerized prescriptions as part of an electronic medical record system.

Each year, more health systems implement computerized order entry systems and more will do so as electronic medical records become more common. “It’s a growth industry,” Kane said.

A small handful of institutions, including Brigham and Women’s Hospital in Boston and Vanderbilt University Medical Center in Nashville, have been leaders in integrating computerized prescriptions, experts say.

It takes 12 to 36 months to implement computerized prescribing system, Gumpper said. Currently, no industry standard system exists. Some hospitals use systems created in-house, while others use commercial products created by companies such as Epic Systems, based in Verona, Wis. or McKesson Corp., based in San Francisco.

Some systems guide doctors through the prescription process, asking questions that might help avoid errors. Some even use voice recognition.

“Patient safety is our final goal,” said Shamliyan.

“Evidence from these studies show that computerized systems can reduce mistakes, but unfortunately less than 50 percent of hospitals have implemented these systems. There is a lot of work to be done in the future.”

The rate of medication errors by hospitals has climbed from only 5 percent in 1992 to nearly 25 percent today. The review found that of these hospitals, CPOE systems were most beneficial when the rate of medication errors was more than 12 percent.

There are two reasons why more hospitals have not switched to electronic prescription systems, says Arthur Levin, director of the Center for Medical Consumers in New York. First, “Physicians, like most of us, don’t like change,” he said. In addition, electronic prescription systems are costly and difficult to integrate into the complex, sometimes-chaotic hospital structure.

Regardless, in hospitals with a computerized prescription system, the number of medication errors dropped, especially among adult patients. However, the rate of one type of error —prescribing the wrong drug — did not decrease, and in five studies, the number of adverse events from drug errors did not decrease.

Each year, more than one-half million patients sustain injuries or die in hospitals from adverse events, according to the study.

Medical schools in the United States rarely address penmanship. It is the same in Russia, says Shamilyan, who studied there. However, at least one medical school in the United States, Indiana University in Indianapolis, teaches penmanship to students in hopes of avoiding errors.

As nearly every industry becomes more computerized, Levin says the doctor’s prescription pad should go the way of scarification used in the 19th century for bloodletting. “Written and verbal orders should be a no-no,” he said.

The Institute of Medicine has already identified medication errors as a major threat to patient safety and has endorsed electronic prescribing of medication as an effective method in correcting the problem.

Medication errors are among the most common medical errors, harming at least 1.5 million people every year, according to the report last year from the Institute of Medicine of the National Academies that was funded by the Centers for Medicare and Medicaid Services.

Senior citizens, because they are the largest consumers of medication, are at the highest risk from these errors.

“Medication errors are a central aspect of improving hospital safety. CPOE can help that process,” says Robert Kane, M.D., review co-author.

“Hospitals would be short-sighted not to use it.” Kane also notes that CPOE systems can be combined with existing computerized medical records, creating a central location for physicians to efficiently enter and view past and present patient prescriptions and medical history.

While the review found that the number of medication errors dropped as a whole, the incidence of one type of error, prescribing the wrong drug, did not decrease.

In five of the twelve studies, the number of adverse events from drugs errors did not decrease. More than one-half million patients suffer injuries or death from adverse events, causing up to $5.6 million annually per hospital, according to the review.

Editor's Notes:

Health Services Research is the official journal of AcademyHealth and is published by Blackwell Publishing on behalf of the Health Research and Educational Trust. Contact Jennifer Shaw, HSR Business Manager, at (312) 422-2646 or jshaw@aha.org. HSR is available online at http://www.blackwell-synergy.com/loi/hesr.

The Academic Health Center is home to the University of Minnesota’s six health professional schools and colleges as well as several health-related centers and institutes. Founded in 1851, the University is one of the oldest and largest land grant institutions in the country. The AHC prepares the new health professionals who improve the health of communities, discover and deliver new treatments and cures, and strengthen the health economy.

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