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Senior Citizen Health & Medicine

Alli Hits Market Today but May Not Be the Diet Pill to Get Hooked On: Consumer Reports

Offers modest results and can cause embarrassing side effects

June 15, 2007 – Senior citizens, more aware of mortality than most, are well aware of the dangers of obesity and, according to those flocking to the reports about the new over-the-counter diet pill, alli, are very interested in maintaining a healthy weight. Alli hits to market today but before getting hooked on the $1.80-per-day-habit, there is information to consider in Consumer Reports that is not all flattering.

 

Related Stories

 
 

Alli Hits the Market by Friday Behind Lots of Hype as First OTC Diet Pill

GlaxoSmithKline says alli designed for overweight adults willing to change how they eat and lose weight gradually – users say it works

June 13, 2007


Does New Over-the-Counter Diet Pill alli Live Up to Its Hype?

OTC strength orlistat works with healthy diet, exercise, study finds

June 13, 2007


Alli Becomes First OTC Diet Pill Approved by FDA

Senior citizens using blood thinners, being treated for diabetes or thyroid disease should consult physician

Feb. 8, 2007


Read the latest news on Senior Health & Medicine

 

The magazine also has a report from June of last year that finds the prescription version of the fat-blocking drug, orlistat (Xenical), hasn't lived up to its promise.

And, CR has a new, quick look at some dieting strategies

Following are some highlights from the articles and links to each one.

Is the new weight-loss drug worth it?

June, 2007 - It's no longer convenient to purchase an effective decongestant these days, now that pseudoephedrine has been moved behind the counter. But if it's weight loss you're after, you can now buy orlistat, a fat-blocking drug of limited effectiveness, with ease. In February the Food and Drug Administration gave manufacturer GlaxoSmithKline the green light to sell an over-the-counter version of the drug under the brand name Alli. Alli is half the dose of prescription orlistat, Xenical, which has been on the market since 1999.

With the move GlaxoSmithKline stands to snag a chunk of the $41 billion that Americans spend on weight-loss strategies each year. The company says Alli, which recenly hit store shelves, will cost $1.80 per day.

But if a pill that limits your body's ability to absorb fat from food seems a little too good to be true, you're on to something. The drug has several drawbacks.

CR's Take

"The prescription fat-blocking drug orlistat (Xenical) is now available in a lower-dose over-the-counter version under the brand name Alli. But it offers modest results and can cause embarrassing side effects, so you might be better off skipping the pills and saving your money."

>> Click to the story at Consumer Reports


Fat-blocking drug: Should you use it?

June, 2006 - What if weight loss were as simple as popping a pill that limits your body's ability to absorb fat from food? By marketing such a drug over the counter, the pharmaceutical company GlaxoSmithKline is wagering that it can snag a chunk of the $41 billion Americans spend on weight-loss strategies each year. And after a thumbs-up from a Food and Drug Administration advisory panel in January, the agency granted conditional approval of the drug in early April 2006.

But ah, yes, there's a catch. The prescription version of the fat-blocking drug, orlistat (Xenical), hasn't lived up to its promise. "In clinical practice, we've found that compliance with orlistat is very poor because of its marginal benefit and tremendous side effects," said Zhaoping Li, M.D., Ph.D., of the clinical nutrition division at the UCLA Medical Center, one of the centers involved in the original trials of orlistat.

At half the prescription strength, the proposed over-the-counter version is likely to be even less effective while continuing to cause the negative effects of the eat-and-excrete approach to weight loss.

>> Click to the story at Consumer Reports


Three diet doubtfuls

Despite the hype, these tactics are unlikely to help

June, 2007 – A quick review by Consumer Reports of some dieting strategies.

Diet pills. Weight-loss pills have a discouraging track record. “Fat burners” such as amphetamines and ephedra have been linked to heart palpitations, strokes, heart attacks, and deaths, even in healthy people.

Angel and devil foods. Some diets allow coffee, and some ban it; the same for milk and fruit. Lists of foods with special powers were part of two diet books we reviewed: The Abs Diet’s “Power 12” and the “Top Ten Sonoma Diet Power Foods.”

The glycemic index. Several of the diet books based their meal plans on the principle of avoiding foods that cause a rapid rise in blood sugar, so-called high-glycemic-index foods. The science behind this is solid.

>> Click to the story at Consumer Reports

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