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Introduced this weekend

Intelligent Pill Dispenser Designed to Assure Senior Citizens Take the Right Pills

June 21, 2004 - A pill dispenser with embedded intelligence that allows remote communications with pharmacists and physicians was displayed this weekend at the American Society of Health System Pharmacists in Las Vegas. The designer says it can help aging patients deal with complex medications.

INRANGE  

The most visible component of the INRange system is the MOD2-10™ delivery module which is placed at a patient’s residence. The MOD2-10 reminds the patient to take his or her medications at pre-scheduled intervals, and it delivers the exact prescribed dose to the patient. In addition, the MOD2-10 takes pre-emptive action if the patient does not adhere to the prescribed medication schedule.

When it is time for an individual user to take his or her medications, the MOD2-10 provides a visual and audible alert. In response to this prompting, the user then presses the red “Drop” key on the control key panel.

The MOD2-10 then moves the appropriate MEDisc™ into position and removes the correct unit dose package. This process is repeated for all medications within the prescribed regimen.

 

The first such system - called INRange Telepharmacy Fulfillment System - has been designed by Mary Anne Papp, D. O., a cardiologist and associate professor of medicine at the Medical College of Wisconsin, and staff physician at Froedtert Hospital.

“Complicated drug therapies are being used to help more patients than ever manage conditions such as diabetes, congestive heart failure, and HIV-AIDS,” says Dr. Papp. “Every patient encounter begins with several medication-related questions that include: ‘What medications do you take? When do you take them? How many are you taking? When did you run out? Who prescribes them?’ The sad fact is that we are asking the questions of increasingly aging patients, with complex medication regimens, patients who often respond with ‘the little blue pills’ or ‘some blood pressure pill.’ ”

“I really hope it benefits us all,” says Dr. Papp, whose invention was inspired by several seniors, including her mother-in-law.

The breadbox sized telepharmacy system uses prescription cartridges that dispense accurate doses and is suited to homes, schools and assisted-living centers. The tightly controlled system enables a pharmacy specialist or clinician to remotely monitor and manage the drug regimens of patients. “A pharmacist in the UK can dispense a single dose of AIDS medication in Somalia using our pharmacy without walls. Not unlike an ATM machine, it dispenses pills instead of dollars,” Dr. Papp says.

It is especially suited for those who are at risk for non-compliance due to visual, auditory or cognitive impairments, the company says. Recent studies show that in-home prescription medication errors are rising, Dr. Papp says. More patients are under prescription drug therapy than ever before, more diseases require complicated drug therapies, and more complex drugs are being prescribed, she points out. “Pharmacists dispense bottles and I wanted them to dispense doses,” says Papp of the impetus behind here idea. “What we need is the hand of a nurse in the home.”

Under a grant to the Medical College of Wisconsin from INRange and Glaxo Smith Kline, Medical College physicians at Froedtert Hospital will soon begin to use INRange Systems for congestive heart failure patients. VA hospitals in St. Louis and Jacksonville already have plans to use INRange.

INRange’s visible component is the delivery module that is placed at a patient’s residence. The module reminds the patient to take their medications at pre-scheduled intervals and delivers the exact prescribed dose.

The invisible component is software that enables a pharmacist or licensed clinician to remotely schedule, change and monitor a patient’s drug therapy and compliance using a wireless communications link to the in-home box. The clinician can access the system using a standard web browser. Connections are controlled using secure encrypted communications, and audit trails are kept by individual users. The prescribed medications are delivered in individualized unit dose packages which are contained in patented medication carriers known as MEDiscs.

INRange Systems can interface with a networked pharmacy system that verifies prescriptions, alters time regimens, locks out dangerous drug interactions and more. The system was honored with the Ben Franklin Technology award for best new idea in January 2002.

Dr. Papp began the project in 1998 while working for the VA Hospital in Chicago then joined forced with the Design Manufacturing and Engineering clinic at her alma mater, the University of Dayton, to develop the first working prototypes that gained patents.

“My inspiration came from my experience with my mother-in-law and countless other seniors who brought me shopping bags full of discontinued or altered dose medications and forgotten refills,” Papp says. “The mechanism inspiration came from the birth control dial-a-paks. Using Sears tools in our basement, my husband and I altered the dispensers to automated radial exit.”

Bob Bogash, past president of the American Society of Health-System Pharmacists refined the device to conform to pharmacy law. Ben Franklin Technology Partners and the Pennsylvania Life Science Greenhouse worked closely with INRange.

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