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Alzheimer's, Dementia & Mental Health

Brain Fitness Program Clinical Trial Attracts 500 Senior Citizens

Program is designed to address the root causes of age-related cognitive decline

  Memory Improvements  
 

Healthy Aging
Studies show the Brain Fitness Program improves memory by 10+ years and significantly increases processing speed in healthily aging adults. Importantly, follow-up testing shows benefits last beyond the end of the program. Results from these studies have been published in the journal Proceedings of the National Academy of Sciences and have been presented at numerous conferences, including the Society for Neuroscience, the company says.

 

Oct. 18, 2007 – More than 500 senior citizens, age 65 and over, have enrolled in a clinical trial of an innovative computerized training program designed to enhance memory. These older Americans are seeking to improve their cognitive health and contribute to scientific research, according to Posit Science Corporation, sponsor of the trial.

The IMPACT ("Improvement in Memory with Plasticity-based Adaptive Cognitive Training") study’s principal Investigators are Elizabeth Zelinski, PhD, of the University of Southern California and Glenn Smith, PhD, Mayo Clinic.

The trial involves measuring the effects of a cognitive training program -- the Brain Fitness Program on memory. Based on the fundamental principles of brain plasticity, the Brain Fitness Program is designed to address the root causes of age-related cognitive decline.

It uses adaptive exercises that target auditory and language systems to drive generalized improvements in cognition.

 

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The exercises are designed to improve the speed and accuracy of information processing in the brain, and engage the brain's neuromodulatory systems, including attention and reward, that contribute to learning and memory.

 

Long-Term Care Insurer Makes Brain Fitness Available to Customers

Dementia, Alzheimer’s the most costly claims for long-term care insurance

In September, a major long-term care insurance provider, Penn Treaty American, announced it would promote brain fitness as a tool to “enrich” its client’s lives.

Penn Treaty is offering thousands of its policyholders the opportunity to try the computer-based mental exercise program, Brain Fitness Program, created by Posit Science Corporation and hailed as one of the “medical breakthroughs of the year” by CNBC.

The program guides users through a series of listen-and-respond exercises designed to improve memory, strengthen communication, and sharpen thinking, with the ultimate goal of delaying the onset of dementia-based impairment.

“We believe that each of our policyholders wants to maintain their independence and health well into their senior years,” said Stephen R. La Pierre, Senior Vice President of Penn Treaty. “We need to be more than just a financial safety net if your health declines; insurers also have a responsibility to coach policyholders in ways of living longer, healthier lives.”

La Pierre says dementia and Alzheimer’s disease are the most extensive and costly causes of long-term care insurance claims.

A proactive cognitive health program can give policyholders the tools they need to actively address their concerns of developing dementia. Such a program may also reduce the frequency and length of future cognitive claims.

“Scientific evidence convinced us that the Brain Fitness Program from Posit Science Corporation could really improve the cognitive abilities of many of our policyholders,” La Pierre said.

In recently published studies, participants using the Brain Fitness Program showed statistically and clinically significant gains on standard cognitive batteries, while participants in control groups showed minimal or no gains. The gains are equivalent to 10 or more years of improved cognitive function (such as ability to remember and faster processing speed) among populations over age 60.

“Penn Treaty was one of the first providers to offer long-term care insurance more than 35 years ago, and continues to be a true leader in this industry,” said Jeff Zimman, CEO of Posit Science.

The Brain Fitness Program is the first component of Penn Treaty’s comprehensive menu of wellness services and programs, which will be rolled out over the next year as part of a greater wellness initiative promoting healthy physical and mental fitness that the Company expects could revolutionize the long-term care insurance industry.

 

This approach, described as "SAAGE" -- for speed, accuracy, adaptivity, generalization, and engagement of neuromodulation -- represents an exclusive approach to cognitive training that goes far beyond general cognitive stimulation.

The IMPACT trial compares the benefits of the Brain Fitness Program to a computer-based learning control matched for computer usage and training intensity. It was chosen to represent current clinical recommendations regarding "staying cognitively active."

Once completed, the IMPACT study will represent the first large-scale randomized controlled trial of a non-invasive cognitive intervention for aging adults that is available for widespread, individual use. In addition to using standardized neuropsychological tests to assess training-related changes in memory, the IMPACT study will also measure the improvements in cognitive abilities directly reported by study participants themselves.

According to a report commissioned by the National Institute on Aging, the U.S. population of adults 65+ will double in size within the next 25 years. By 2030, almost 1 in 5 Americans -- approximately 72 million people -- will be 65 years or older. Today's older Americans are much different from their predecessors -- they live longer, have lower disability rates, demand higher levels of healthcare, and are significantly more proactive in identifying, evaluating, and providing for their own health -- both physical and cognitive.

"Not all programs positioned as brain training are alike," says Principal Investigator Dr. Elizabeth Zelinski of the Andrus Gerontology Center at USC.

"The Brain Fitness Program is the first widely available program to go beyond train-to-the-task approach and really address the underlying brain functions that scientists believe lead to changes in memory with age."

The hope is that the Brain Fitness Program will demonstrate improvements in standard clinical tests of memory, but also show that individuals feel more vital and confident after use, says Zelinski. "Our obligation, as cognitive psychologists, is to really put these programs to the test and evaluate their efficacy," continues Zelinski. "The implications for a truly effective brain fitness training program on the cognitive health of seniors would be enormous."

About Posit Science

Posit Science Corporation develops science-based brain health programs. The company works with more than 50 brain scientists from leading universities around the world to create training programs that enhance cognitive performance. Its assessments and exercises are based on neuroplasticity the -- brain's ability to "rewire" through intensive, repetitive and progressively challenging activity.

The company's Brain Fitness Program is distributed without charge by Humana to its Medicare Advantage members, is licensed to more than 100 retirement communities nationwide, is sold online and by Authorized Providers.

Posit Science has received several grants from the National Institutes of Health (NIH). Posit Science was named "Best Small Company" by the American Society on Aging, was named "Best Fitness Initiative" by the Consumer Health World Conference and was selected as one of the "medical breakthroughs of the year" by CNBC. For more information visit http://www.positscience.com/.

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