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Today is Wednesday, November 12, 2008

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How Does Genetics Influence Healthy Aging?

Alliance For Aging Research Launches Innovative Web Feature, Genetics In Aging

March 28, 2001 -- A revolution is underway in science, technology and medicine that will dramatically improve our health spans and aging processes, and will likely alter our perceptions of when "old age" begins. Lifesaving breakthroughs in genetic research will change the way we diagnose, treat and prevent disease. 

To help families understand the role of genetics in the aging process, and just what is known about their DNA and what it might mean for them, the Alliance for Aging Research (www.agingresearch.org) today launched Genetics in Aging, an innovative web feature located at http://www.agingresearch.org/geneticsinaging/index.html .

"Genetics in Aging bridges the education gap for people who are concerned about their chances for healthy aging and the possible links of inherited disease," said Daniel Perry, executive director of the Alliance for Aging Research. "This new feature will show how your genetic heritage and lifestyle habits relate to your personal health risks. Understanding the interplay between your body's genetic 'roadmap' and life choices can improve your odds of leading a more vital, productive and independent life."

Excitement is growing in the scientific and medical communities due to the progress of the Human Genome Project (HGP), a decade-long effort to characterize - for the first time ever - the complete set of genetic instructions encoded in the three billion base pairs of human DNA. Scientists expect the project to yield a bountiful harvest of new cures and preventions of disease, including genetic treatments for illnesses such as prostate cancer, diabetes, and neurodegenerative disorders like Parkinson's and Alzheimer's. "Genetic research will revolutionize medicine by giving health care providers precise diagnostic, therapeutic, and prevention tools," said Perry. "The endless promise of genetic research may one day enable doctors to correct flaws in a person's genetic makeup by replacing abnormal genes with normal ones, provide medicines that fit an individual's systemic makeup and attack the cause of illness rather than its symptoms, and eliminate adverse drug reactions that so commonly plague patients today."

Genes tell cells how to behave, and influence everything from what you look like to what diseases you may get. Problems arise when genes are malformed or defective, causing the development of cancer, diabetes, and many other illnesses. The cause of age-related illnesses, however, is usually attributable to the interaction of genetic predisposition and environmental factors, such as diet and exercise.

Genetics in Aging will educate visitors about genetics research, current and possible future discoveries, and how this breakthrough science will impact the aging population. While not a diagnostic tool, Genetics in Aging highlights the importance of genetics in disease susceptibility and the need to design appropriate treatments.

Broken into two parts, Genetics in Aging includes:

DNA Basics, which provides an introduction to the world of genetics; and Diseases and Conditions, which allows visitors to explore what is known about the genetic components of Alzheimer's and Parkinson's disease, breast cancer, colon cancer, prostate cancer and coronary heart disease - all of which are significant to the aging population. To develop Genetics in Aging, the Alliance received an unrestricted educational grant from DNA Sciences, Inc., an integrated genetics discovery company based in Fremont, Calif. DNA Sciences is focused on identifying the genetic basis of disease susceptibility, disease progression and response to drug treatment. The DNA Sciences Gene Trust Projectsm provides consumers with an opportunity to participate in this effort by volunteering a small blood sample for genetics research.

"While we cannot put a timeline on discovery, we are at a historic point in the life sciences and on the brink of uncovering just what makes the body tick at the cellular and molecular levels," said Perry. "Having a full understanding of our genealogy and how best to treat genetic diseases will bring breathtaking changes to the meaning of 'old age.'"

A non-profit, independent organization, the Alliance for Aging Research is dedicated to improving the health and independence of Americans as they age through public and private funding of medical research and geriatric education.

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