Aggressive Microdermabrasion Induces Wound-Healing
Response to Repair Aging Skin
Aggressive treatment may be a useful procedure to
stimulate remodeling and to improve the appearance of aged human skin
Microdermabrasion treatment at The New You Med Spa. See more
below news report.
Oct. 19, 2009 A hot technique for rejuvenating
aging skin just got hotter with the release of a new scientific study
confirming that microdermabrasion, using a coarse diamond-studded wand,
appears to induce molecular changes in the skin of older adults that
mimic the way skin is remodeled during the wound healing process.
"Microdermabrasion is a popular procedure for skin
rejuvenation," the authors write. "It has been suggested that
microdermabrasion can improve the appearance of wrinkles, atrophic acne
scars, dyspigmentation and other signs of aging skin."
The procedure involves buffing the skin using
grains of diamond or another hard substance.
In order to objectively
change the appearance of wrinkled skin, such a procedure would have to
induce the production of collagen, the major structural protein in the
skin, according to the report in the October issue of Archives of
Dermatology, one of the JAMA/Archives journals.
Previous studies have shown that microdermabrasion
using aluminum oxide may not always stimulate collagen production;
whether more aggressive but still nonablative (not involving the
destruction of skin tissue) methods could consistently do so is unknown.
Darius J. Karimipour, M.D., and colleagues at the
University of Michigan, Ann Arbor, conducted a biochemical analysis of
skin biopsy specimens before and four hours to 14 days after a
microdermabrasion procedure.
The significance of this study lies in the fact
that this procedure is minimally wounding, says
Darius J. Karimipour, M.D., who conducted the
research while a clinical assistant professor in the
University of Michigan Health Systems department of
Dermatology. He now has a private practice.
Healing occurs in the
course of a day instead of weeks to months as is
seen with other procedures that improve sun-damaged
skin, he adds.
Forty adults age 50 to 83 years with
sun-damaged skin on their arms volunteered to participate in the study.
Each underwent microdermabrasion with a diamond-studded handpiece of
either a coarse-grit or medium-grit abrasiveness.
When performed with the coarse-grit handpiece,
microdermabrasion resulted in the increased production of a wide variety
of compounds associated with wound healing and skin remodeling. This
includes cytokeratin 16, a well-characterized response to injuries to
the skin's outer layer; antimicrobial peptides that fight infection;
matrix metalloproteinases that break down skin's structural proteins to
allow for rebuilding; and both collagen precursors and other substances
that form the pathway to its production.
These molecular changes were not seen in
individuals who received microdermabrasion using the medium-grit
handpiece, the authors note. All patients experienced a mild period of
redness that typically lasted less than two hours.
"We demonstrate that aggressive nonablative
microdermabrasion is an effective procedure to stimulate collagen
production in human skin in vivo," they write. "The beneficial molecular
responses, with minimal downtime, suggest that aggressive
microdermabrasion may be a useful procedure to stimulate remodeling and
to improve the appearance of aged human skin."
This study was supported by a Dermatology
Foundation Clinical Career Development Award in Dermatologic Surgery to
Dr. Karimipour and by a University of Michigan Human Appearance Research
Fund to the Department of Dermatology.
About Microdermabrasion
By American Society of Plastic Surgeons
Microdermabrasion is a skin-freshening technique
that helps repair facial skin that takes a beating from the sun and the
effects of aging. The plastic surgeon uses a device like a fine
sandblaster to spray tiny crystals across the face, mixing gentle
abrasion with suction to remove the dead, outer layer of skin. As with
other skin rejuvenation techniques, more than one treatment may be
needed to reduce or remove fine wrinkles and unwanted pigmentation.
By Dr. Brian Zelickson, University of Minnesota
Medical School, Dermatology
When people refer to 'Microdermabrasion' they are
referring to a whole class of devices which remove a very superficial
portion of the skin, usually just the stratum corneum. This can be done
through a number of different methods and techniques. Some
microdermabrasion devices utilize abrasive paddles or crystals that are
passed along the surface of the skin with a suction hand piece which
removes the dead skin layer. Other methods use creams with abrasive
particulates that are rubbed onto the skin.
Your physician may be more or less aggressive with
microdermabrasion and do it in combination with other techniques, like
chemical peels in an attempt to get greater results.
Microdermabrasion Advertising by The New You Med
Spa
Fine lines getting you down? Looking for a solution
to dull, aging skin that doesn't include painful procedures or recovery
time? Microdermabrasion is a non-invasive solution that revitalizes your
skin's appearance, promotes production of new cells in the deepest skin
layers, cleanses pores, and stimulates collagen networking, all
resulting in improved skin texture and appearance. Microdermabrasion
uses a fine jet of crystals to gently and painlessly exfoliate your skin
while vacuum suction removes the crystals with the dead skin cells.
You're left with new, softer skin and an even skin texture. For the best
results we recommend 4-6 microdermabrasion treatments. New patient
Microdermabrasion is $50.00 with complimentary consultation.
