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Aging News & Information
Hebrew Student to Patent Antioxidant Method to
Retard Skin Wrinkles
Doctoral candidate sees a new generation of cosmetic
products
Aug.
30, 2007 A doctoral candidate at Hebrew University envisions a new
generation of cosmetic products from her discovery of a new method to
stop skin wrinkles. It not only combats wrinkles, it is more effective
against deeper levels of wrinkles than current products, she says. But,
she is not telling the plant source she used to develop the
antioxidants, since here commercial patent is pending.
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Dr. Bossi is looking towards a new generation of
cosmetic products which will not only combat wrinkles but will be more
effective against deeper levels of skin wrinkles than current products.
Dr. Bossi did not reveal the plant source she used to derive the
antioxidant, since the research is in the process of being patented.
A new method for fighting skin wrinkles has been
developed at the Hebrew University Faculty of Agriculture, Food and
Environmental Quality Sciences.
Dr. Orit Bossi succeeded in isolating a plant-based
antioxidant that delays the aging process by countering the breakdown of
collagen fibers in the skin.
Antioxidants operate against free radicals which
cause a breakdown of many tissues in the body, including the skin. When
found in small quantities in the body, free radicals are not harmful and
are even involved in various physical processes.
When there is an excess of free radicals, however,
as occurs during normal aging or as a result of excessive exposure to
ultra-violet radiation from the sun, the result, among other things, is
a breakdown of the collagen (a fibrous protein found in skin, bone,
cartilage, tendon, and other connective tissue) and elastin (a protein
that is the main constituent of the elastic fibers of connective tissue)
fibers in the skin.
When this happens, there is a loss of skin
elasticity and the formation of wrinkles.
A problem with many of the commercial antioxidants
found today in the market that are said to retard the aging process is
that they oxidize quickly and therefore their efficiency declines with
time, said Dr. Bossi.
Vitamin C, for example, oxidizes rapidly and is
sensitive to high temperatures. This is also true of the antioxidant
EGCG which is found in green tea, and vitamin E. As opposed to these,
the antioxidant which I used in my research is able to withstand high
temperatures, is soluble in water, and does not oxidize easily and thus
remains effective over time.
In her research, Dr. Bossi conducted experiments on
mice skin tissue, which, she says, resembles that of humans. She applied
her antioxidant on two skin cell groups those which had been exposed
to the suns rays and received her antioxidant and those which also had
been exposed to sun but did not receive the antioxidant. The untreated
cells showed a rise in free radicals causing wrinkles, while those cells
which had been treated showed no significant increase in the free
radicals level.
Dr. Bossi conducted her doctoral research under the
supervision of Zecharia Madar, the Karl Bach Professor of Agricultural
Biochemistry at the Hebrew University, and Prof. Shlomo Grossman of Bar-Ilan
University.
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