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Saturday, July 05, 2008

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Aging in Men Advances with Loss of Sleep

August 16, 2000 - A new study reports that lack of deep sleep contributes to the aging of males. 

Sleep, which affects the regulation of growth hormone and cortisol secretion in young adults, decreases in duration and diminishes in quality with normal aging. (Article in the Journal of the American Medical Association)

In this cross-sectional study of 149 healthy men aged 16 to 83 years, Van Cauter and colleagues found that from early to mid-adulthood, deep slow wave sleep and growth hormone secretion decreased markedly, but total sleep, sleep fragmentation, REM sleep, and cortisol secretion did not change. 

From midlife to late life, REM sleep decreased, wake time increased, and nocturnal cortisol release increased. In an editorial, Blackman reviews the effects of aging on sleep regulation, age-related changes in neuroendocrine function, and their interrelationship.

> AP Story

> Abstract of JAMA Report

> Full JAMA Report

> JAMA Editorial